WOULD you like to lie around all day and achieve the honed, healthy body of a gym bunny, just by popping a pill?
Researchers from the University of MI suggest that the naturally occurring Sestrin protein appears to mimic the effects of exercise on flies and mice in their experimental trials.
These findings could have benefits for fitness, medical, and scientific fields.
"Researchers have previously observed that Sestrin accumulates in muscle following exercise", said Myungjin Kim, research assistant professor in the Department of Molecular & Integrative Physiology. Flies without sestrins did not develop with exercise.
Taking advantage of Drosophila flies' normal instinct to climb up and out of a test tube, their collaborators from Wayne State University in the U.S. developed a type of fly treadmill. About a of those flies had been popular, while others had been particularly bred to lack the ability to salvage Sestrin.
"Flies can usually run around four to six hours at this point and the normal flies" abilities improved over that period.
Researchers at the University of MI have found that a naturally occurring class of proteins, Sestrin, can greatly mimic the effects of exercise in flies and mice.
Australia record easy 10-wicket win over India in first ODI
The duo chased down the below-par 255 run total in just 37.4 overs easily as they remained glued to the middle till the very end. It marked just the fifth time Australia's two openers have scored centuries in the same innings of a one-day worldwide .
28-Year-Old Panthers Linebacker Luke Kuechly Shockingly Retires From NFL
This is yet another in a long line of prominent National Football League players announcing their retirement before the age of 30. Replacing Kuechly at this stage of his career, still seemingly in his prime, will be hard for the Panthers.
'Operation Rock Wallaby' rains food down on wildlife hurt by Australian bushfires
The region's rock wallabies were already "at-risk" prior to the bushfires because of ongoing habitat destruction and drought. With the fire season expected to rage for the next few months, Australians are doubtful that wildlife will fully recover.
Blogging and posting articles for over 9 years, Rada Mateescu is especially enthusiastic about technology, science, and health-related issues. They needed to find flies and encourage them to work out.
Furthermore, when researchers provided one other personnel of frequent, un-educated flies with a max dose of Sestrin, these flies immediately modified into extra adept at the treadmill, and total bodily superior to other flies, even the flies that had appropriate spent three weeks coaching.
The researchers also found that triggering overexpression of Sestrin in the muscles of normal flies and maximizing their Sestrin levels gave those flies greater abilities than the trained flies, even without exercise. The researchers made a decision to experiment with flies and mice to find out more about the connection with sport.
"We suggest that Sestrin can coordinate these biological activities by turning various metabolic pathways on or off", Lee said in a university press release.
In addition to being used by the Average Jane or Joe to keep fit, it could also be used to treat maladies brought upon by old age, disease, or injury, such as loss of muscle mass/strength; for example, preventing atrophy in immobilized muscle groups, such as when a broken limb is put in a cast or natural muscle loss brought about by the aging process. "This type of combined effect is important to get the effect of the training".
For now the researchers top priority is to identify how exactly exercise produces Sestrin within the body.
"Here's extremely extreme for future notion and might perchance well also lead to a medicines for folk that can not exercise", Kim concludes.