Citing several sources with knowledge of the matter, the Financial Times report that Nissan's plan involves a complete split in engineering and manufacturing from Renault, as well as new changes to the Japanese automaker's board.
Nissan, in response to "speculative worldwide media reports", said it was "in no way considering dissolving the alliance".
Nissan issued a statement saying it is "not considering splitting the alliance" and insisted the partnership is its "source of competitiveness".
Long-standing tensions in the Franco-Japanese partnership have been heightened since Ghosn's arrest in Tokyo in November 2018 on allegations of financial misconduct, which he denies.
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The plans for independence had been accelerated by the Japanese company since former chairman Carlos Ghosn fled Japan, where he was accused of financial crimes, to his childhood home of Lebanon, the paper reported. This has reportedly accelerated since Ghosn fled charges of financial misconduct in Japan late past year.
The Financial Times added that in the event of the alliance's relations being terminated, the vehicle manufacturers will have to look for new partners to survive the competitive market.
The alliance's new chief, Jean-Dominique Senard, earlier hit back at the reports of a planned split, telling Belgian daily L'Echo the claims had "no connection to the current situation of the alliance". "Soon we will show you why", he said in an interview published Tuesday. It was said I resigned, that's not true. Nissan's decision to split would mark the end of almost two decades of co-operation.
The alliance rebranded itself as the Renault-Nissan-Mitsubishi Alliance in September 2017, following Nissan's acquisition of a controlling stake in Mitsubishi in 2016.