Liverpool boss Jurgen Klopp responded to the jibe yesterday by suggesting he didn't believe Guardiola had made the remark until he saw it on television and then claimed his rival spends too much time talking about the Reds, with the City manager keen to pour praise on his side's Premier League title rivals in comments that appear to be an attempt to backtrack from the negative remarks that have caused such a stir.
Despite having just finished a game of their own last Saturday, Pep Guardiola was quick to call out Liverpool in his post-match interview.
Klopp was pressed on the looming clash with City, though, as Liverpool remain six points clear at the top of the league table.
The 27-year-old Senegalese forward was booked in Liverpool's stunning 2-1 victory over Aston Villa for simulation - a charge his manager Jurgen Klopp felt was dubious.
Guardiola said it was not a surprise that Mane had rescued a result for Liverpool, "because he is a special talent".
"My son and my daughter all the time when they [Liverpool] win in the last minutes, ask me how lucky they are and I say at the time 'it's not lucky, '" Guardiola told a news conference on Tuesday.
"Regardless of the great thing about Man Metropolis, and that is one thing I've already stated and don't care if followers prefer it or not, there's one thing about Man Metropolis that resembles a Frankenstein membership - they've simply purchased every little thing".
"Sometimes he has this talent to score incredible goals in the last minute". Do I like what he says about my players?
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"In the 94th minute like it was against Leicester, it was a penalty, it was "wow".
'For Jurgen it (the Leicester decision) is a penalty, for the referee it was a penalty, for the VAR it was a penalty.
"So I do agree with that, I think Mane's probably the most in-form out of the three at the moment".
'I didn't listen to what he said so I don't know, ' Guardiola said, wanting to diffuse an escalating situation ahead of Sunday's titanic clash at Anfield. "When he says he's not like this, he's not like that". It happens many times in Anfield, and away, because they push and they push.
"But my comments - that speech was long".
"One of the good things about Klopp and Guardiola over the last few years is we didn't have that rhetoric of the Mourinho way, the Machiavellian way and Ferguson had it as well - that was part and parcel of every build-up of almost every match".
"We have sometimes had our disagreements, but it remains a great pleasure to play besides him because I have the feeling we speak the same type of football".
"I am 100 per cent sure if something like this happened to Man City, they would want to have a penalty".