Detroit's defense simply couldn't get Cousins off the field on Sunday.
Kirk Cousins completed 24 of 34 passes for 337 yards and four touchdowns and hit Stefon Diggs on a key 67-yard pass with just over 2 minutes to play.
The Vikings (5-2) have won three consecutive games in part because their quarterback is making plays to complement one of the NFL's top defenses.
After spending the majority of his career with the Minnesota Vikings as an elite pass-catcher, he has been relegated to blocking duty in Minnesota's run-first offensive attack.
According to the Lions' public relations staff, Stafford reached 40,000 career passing yards in is his 147th career game played, which is the fewest games needed in National Football League history to accomplish the feat.
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They were held to a 0-0 draw in the Carabao Cup by Colchester United and were knocked out on penalties by the League Two club. Spurs looked on their way to another defeat on Saturday, this time against the Premier League's last-place team in Watford .
It has taken Matthew Stafford 147 career games to reach the 40,000 yard status.
Cousins picked the Lions apart all day as Detroit failed to mount any semblance of a pass rush, and Cook ran for 142 yards and two touchdowns on 25 carries. Not too shabby. Stafford has already thrown for over 100 yards in the first quarter today.
Amendola led the Lions with 105 yards on eight catches, and Marvin Jones caught four touchdown passes, including a 2-yarder with 3:05 to play that gave the Lions a wisp of hope. Diggs had seven receptions for 142 yards.
Stafford was 30 of 45 for 364 yards with four TD passes and an interception on his last possession.
Lions: RB Kerryon Johnson (knee) and CB Darius Slay (hamstring) were injured during the game and did not return. DE Everson Griffen limped off the field in the third quarter.
So following their win over the Lions on Sunday, what are some of the biggest takeaways from the Vikings' latest victory of the season?