Dr Sundeep Salvi, Director, Chest Research Foundation, and an expert on the national steering committee to prevent air pollution, said the study has highlighted for the first time that household air pollution is also a leading risk factor for heart disease and deaths in India.
Globally, however, cardiovascular disease remains the main cause of death among middle-aged adults, accounting for 40 per cent of all deaths, compared with 26 per cent for cancer.
For this paper, the research involved more than 162,500 adults aged 35 to 70 from 21 countries who were followed for a median of 9.5 years.
Cancer is now the leading cause of death in high-income countries, while cardiovascular disease continues to be the biggest killer in poorer nations.
Most cancers has overtaken coronary heart illness because the main reason for loss of life in rich worldwide locations and will change into the world's greatest killer inside just some many years if present developments persist, researchers mentioned on Tuesday.
In high-income worldwide locations, frequent remedy with cholesterol-lowering statins and blood-pressure medicines have helped carry charges of coronary heart illness down dramatically up to now few many years.
The researchers additionally discovered that heart problems were more widespread in middle-income and low-income countries than in high-income countries. It was estimated that 55 million deaths occurred in the world in 2017, of which approximately 17.7 million were due to CVD.
In low-income countries, however, heart disease proved more deadly, causing 3.7 per cent of deaths compared to 1.3 per cent by cancer.
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'The fact that cancer deaths are now twice as frequent as cardiovascular disease [CVD] deaths in high-income countries indicates a transition in the predominant causes of death in middle age, ' said Professor Salim Yusuf.
In poorer nations, the reverse is true - with cardiovascular disease three times more likely to claim the lives. The study was led by Dr. Gilles Dagenais, emeritus professor at Laval University in Quebec, Canada.
These included diet, behavioural and socioeconomic factors, they said.
Dr. Philip Joseph, Associate Professor of Medicine at McMaster University and the co-lead of the paper concluded: "Efforts to tackle CVD through focusing on a small number of behavioural risk factors, such as reducing smoking, are important, but these efforts should expand to better Blood Pressure control and better use of secondary prevention, with simple and effective low-priced medications".
However, the relative importance of risk factors for CVD cases and death varied widely between countries at different stages of economic development. "There is an opportunity now to realign global health policies and adapt them to different groups of countries based on the risk factors of greatest impact in each setting".
Stephanie Read of Women's College Research Institute in Toronto and Sarah Wild of the University of Edinburgh, U.K., wrote a journal commentary published with the research.
Countries analysed in these two reports from the PURE Study include: Argentina, Bangladesh, Brazil, Canada, Chile, China, Colombia, India, Iran, Malaysia, Pakistan, Palestine, Philippines, Poland, Saudi Arabia, South Africa, Sweden, Tanzania, Turkey, United Arab Emirates, Zimbabwe.