The officials would not provide details of where or when Hamza bin Laden died or whether the United States played a role in his death.
The State Department in February had offered a $1 million reward for information leading to Usama bin Laden's son.
He was perceived as the apparent heir to lead Al Qaeda and had threatened to attack the United States.
Born around 1989 in Jeddah, Saudi Arabia, Hamza has been wanted by the Federal Bureau of Investigation for ties to terror groups for some time.
NBC News said three USA officials had confirmed they had information of Hamza bin Laden's death, but gave no details of the place or date.
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Last August, it was revealed Hamza had married the daughter of Mohammed Atta, the lead hijacker in the 9/11 terror attacks. Letters seized from the compound suggested the elder bin Laden wanted his son to join him in Abbottabad and was grooming him as a leader. It is unclear when or where the operation took place, although bin Laden was reported to be in either Pakistan or Afghanistan.
Hamza, believed to be about 30-years-old, was at his father's side in Afghanistan before the September 11 attacks on the USA, and spent time with him in Pakistan after the US-led invasion of Afghanistan pushed much of al Qaeda's senior leadership there, according to the Brookings Institution.
In May 2016, he urged fighters in Syria to unite and "liberate Palestine", while he also warned Americans they would be targeted.
Since U.S. Special Forces killed bin Laden during the famous raid on his Pakistani compound in 2011, there have been questions around who could fill his void in Al-Qaeda.
Hamza appeared in several propaganda videos for the terrorist group.
A piece written by counterterror expert and former Federal Bureau of Investigation agent Ali Soufan warned that "Hamza is being prepared for a leadership role in the organization his father founded".