Right-back Wan-Bissaka is one of United's principle transfer targets and the club made their first move for him earlier this month, which Palace swiftly turned down.
Other potential right-back targets for United are Paris Saint-Germain's Thomas Meunier and Tottenham's Kieran Trippier.
However, Wan-Bissaka still has three years left on his current contract at Selhurst Park and Palace are desperate to keep him so the Metro claim the Londoners are demanding at least £50m for his signature.
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The 21-year-old made the second highest number of tackles (90) and interceptions (84) in the entire English top flight this season, and is now on worldwide duty with the England U21 side.
Should they pay the £60m Palace want?
The Slovenian only signed a new four-year contract in April but it's understood that United have been sounded out about triggering the £107m buyout clause if they decide to sell David de Gea. "It says I am going to be there, so that is all I can focus on now".
Wan-Bissaka clocked 39 appearances for the Eagles over the course of the season.