SANA, Syria's state news agency, quoted a Syrian military source who said that the air defense system was activated against missiles fired at western Damascus from the direction of Quneitra, in the occupied Golan Heights.
On January 12, 2019, Syrian air defences shot down Israeli missiles targeting a transport ministry warehouse at the Damascus worldwide airport, SANA reported at the time.
This still image from Syrian state television channel SANA shows the night sky with a point of light firing up into it and the sound of shooting.
"They were Israeli strikes that targeted the Kiswah region where weapons warehouses belonging to Iran and [its Lebanese proxy] Hezbollah are located", observatory head Rami Abdel Rahman said.
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There was no immediate comment from Israel, but it has been increasingly open in recent months about targeting sites in Syria that it says are connected to Damascus' close allies Iran and Hezbollah.
A UK-based activist group claimed that several Iranian fighters were killed in the April attack. Iran and Hezbollah have played a key military role in helping Syrian President Bashar al-Assad fend off rebels in an eight-year war.
While Israeli air strikes into Syrian territory happen on a fairly frequent basis, the alleged strikes on Friday come amid heightened tensions between Iran and the United States.
Israel insists that it has the right to continue to target positions in Syria held by Iran and its Lebanese ally Hezbollah. "That would be the worst-case scenario, that it expands and affects all kinds of civilian populations in a number of countries".