"Quarantine is a word that people respond to very strongly, but it's actually one of the strongest tools in the public health tool kit", Katz said.
They say proof will be required, and that those who do not comply will be vaccinated immediately, regardless of their religious views.
A tracking map on MarineTraffic.com shows the vessel left the port city of Castries on St. Lucia last night and is due to arrive at Willemstad, Curacao, on Saturday morning.
CNN reported the ship had left St. Lucia, and online ship traffic data showed that the vessel was under way and headed for the island of Curacao.
It is normally docked in Curacao when not in use, but Church officials have not returned messages for comment.
"The confirmed case as well as other crew members are presently stable, but remain under surveillance by the ship's doctor", she said, noting the incubation period of measles is 10 to 12 days before symptoms appear.
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The ship departed Curacao for the nearby island of St Lucia on April 28.
The Freewinds, with approximately 300 crew members and passengers, has been quarantined in a port in the Caribbean island's capital since officials discovered the person on board has the highly contagious disease, according to Chief Medical Officer Dr. Merlene Fredericks-James. Curacao health officials then alerted authorities in St. Lucia.
Symptoms include runny nose, fever and a red-spotted rash. Most people recover, but measles can lead to pneumonia, brain swelling and even death in some cases.
The number of measles cases in the United States has reached a 25-year peak with more than 700 people diagnosed as of this week, part of an global resurgence in the disease.