Inoue, however, is expected to relinquish his WBA belt as it will be "unified" with Donaire's super belt in the WBSS final to be held later this year.
"This is what we have been waiting for". This was the best fighting the best.
The three division world champion has fought the majority of his bouts in his home country of Japan, tonight will be his first time fighting in Europe when he steps into the SSE Hydro ring in Scotland.
"In the first round, it was a different environment for me and I had to make some adjustments", Inoue said at a news conference.
Inoue, a 5-foot-5, baby-faced assassin from Yokohama who has won world titles in three weight divisions, will begin the final as favorite after this swift demolition and thrilling exhibition of his punching power, timing and speed.
I always felt like I could knock him out and thats what I fought for, said Inoue. They put on a show.
"I think Inoue is going to win because he is on the way up and still improving while Donaire has reached his peak", said Cataraja. "I'm really glad I was able to do that and pull off a good performance", said Inoue, known to fans by the nickname "Monster".
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Inoue landed the better shots in the opener, immediately causing Rodriguez problems with his impeccable timing and lightning-fast punches.
The second round was a massacre.
As it pertains to his future, the night ended with the latest step in the destructive path of Naoya Inoue (18-0, 16KOs), who scored a 2nd round knockout of Emmanuel Rodriguez.
Rodriguez was left shaking his head and wincing in pain as he knelt on the canvas before getting up at the count of eight.
In his last fight, against Ryan Martin, the 28 year old was able to ease into the semi-final with a comprehensive schooling.
On the undercard, England's Paul Butler (29-2, 15 KOs) finished Mexico's Salvador Hernandez Sanchez (14-9-1, 9 KOs) with a left hook to the body in Round 6. McDonnell was granted the daunting task of defending the WBA title against Inoue, in the Japanese fighters first fight in the division, and was caught nearly immediately by a mini-flurry of punches that dropped him to the canvas.