"@AntoGriezmann He has informed the club that he will not continue as rojiblanco next season", a tweet read.
"The truth is it has been hard to arrive to this point but I feel it's what I need to do, I want to thank you for all the support you have given me in these five years, where I won my first trophies. They have been five unbelievable years in which I have left everything on the pitch".
Barca look certain to be his next destination with Griezmann, 28, reportedly set on making a move he spurned a year ago.
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Griezmann issued a statement on his imminent departure in a length video on Atletico's official Twitter account, in which he thanked the club's fans for all the support they've given him down the years.
"[I want] to tell you I have taken the decision to leave".
Don't count out the interest of teams like Manchester United, in need of a summer makeover, and Paris Saint-Germain if Neymar happens to leave, though that feels unlikely.
The Frenchman has scored 133 goals in 256 appearances for Atletico since joining from fellow Spanish outfit Real Sociedad in 2014.
"I know Antoine is very happy in Madrid and that he is very well there".