Morgan responded by not only doubling down on his Little Mix and DeGeneres comments but also slamming Ariana for "using nudity to sell records".
His criticism of the girl pop group comes just days after he criticised DeGeneres for a video she shared in honour of International Men's Day.
And Ariana was quick to back up Joan after Piers tweeted her back, saying: "Hi Joan, my mother taught me to speak my mind & never be afraid to express honestly held opinion".
Ariana Grande had some strong words for Piers Morgan after the journalist launched a Twitter tirade on Wednesday against the United Kingdom girl group Little Mix and her mother, Joan Grande.
Grande, 25, then chimed in, tweeting: "Ellen is an incredible and kind human being".
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"As your own daughter does.!" he added, attempting to curry favor with Grande. Of course, women can do what they like - but if they/you use nudity to sell records to impressionable young female fans, I'll continue to call them/you out on it.
Grande quickly jumped on Twitter, calling out Morgan for his views writing, "I use my talent AND my sexuality all the time because I choose to".
WAR: Piers and Ariana were in a heated argument (Pic: TWITTER) SLAMMED: The pair were throwing hits to each other on Twitter (Pic: GETTY) "All due respect, but thank YOU".
"We will keep fighting 'til people understand".
Grande ended the conversation by calling out Morgan's double standards by sharing his tweet of a semi-nude photo of himself in front of a fireplace.
"When u do it it's ok tho right?", she wrote.
Morgan also invited Grande to go on Good Morning Britain to "settle this like mano-to-womano".