The Americans won two of three matches and tied the other in foursomes.
Brandon Wu and Alex Smalley got the first point on the board for the us on Sunday, rallying from 2 down after seven holes to beat Alex Fitzpatrick and Conor Purcell, 2 and 1.
The Americans won the amateur competition for the second straight time and now lead the series 37-9-1.
Alex Fitzpatrick and Conor Purcell embrace after scoring the first point of the day beating United States of America during day one of the 2019 Walker Cup at Royal Liverpool Golf Club, Hoylake.
The all-English pairing of Conor Gough and Harry Hall were never behind in their match against Akshay Bhatia and Stewart Hagestad.
Great Britain and Ireland captain Craig Watson consoles Alex Fitzpatrick after he lost his singles match
The Americans actually earned more points in foursomes this weekend, 4.5-3.5, and if they end up winning it all they will be the 11th team in the past 12 Walker Cups to win more foursomes points and capture the Cup.
They were four-up after eight holes and although the Americans cut the deficit in half by winning at the 13 and 15, the remaining holes were halved to give the home side the early breakthrough. Smalley missed that putt, but the Americans still took the hole and their first lead.
Scott then claimed a notable scalp for GB&I, defeating US Amateur champion Ogletree by one hole in a match where the Nairn golfer fired in six birdies.
"They've got a great memory now", US captain Nathaniel Crosby said.
John Pak and Brandon Wu levelled up the match, with Pak defeating Amateur champion James Sugrue by a single hole and Wu easing to victory over Tom Sloman 4&2.
Crosby has remained confident in regard to the two, which is why he'll send them out in the final two singles matches - Hammer will face Purcell in the penultimate match while Fisk will be in the anchor spot opposite Sloman.
Captain Craig Watson's decision to pair compatriots Scott and Walker looked promising as they birdied the third, fourth and fifth in the second game to be one up on the seventh tee. Norman Xiong (3-0-1) also didn't lose a match.
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