With the reigning Premier League champions tied 2-2 with Tottenham in the dying minutes of the match, Gabriel Jesus appeared to snatch all three points with a victor in the second minute of stoppage time.
Speaking to Sky Sports, Lloris admitted: "To be honest I thought it was a goal".
Gabriel Jesus of Manchester City celebrates after scoring his sides third goal which is later disallowed by VAR during the Premier League match between Manchester City and Tottenham Hotspur at Etihad Stadium on August 17, 2019 in Manchester, United Kingdom. It's the second time, it's tough.
Fully fit again after a last season's frustrating injury issues, De Bruyne has already created the same number of assists in the first fortnight of this term- three - that he did in the whole of the 2018/19 Premier League campaign.
The drama and controversy will overshadow an excellent encounter which City dominated for large stretches, playing what Guardiola said was some of the best football under his charge.
The initial feeling behind the substitution was Guardiola being upset with Aguero's defending in the build up to Moura's goal, but that couldn't be any further from the truth as a frustrated Guardiola explained post-match.
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But Adrian was guilty of a mistake in the 83rd minute when he hit a panicked clearance against Danny Ings, the ball bouncing off Southampton's former Liverpool striker into the empty net.
He can not stop scoring in the Premier League, either.
"The guys are creating chances - I could have scored more", Pukki said. He was tied as the top scorer last season with Liverpool attackers Mohamed Salah and Sadio Mane.
The headlines show there were two goals apiece with both sides claiming a point.
Sterling meanwhile also maintained his own superb start to the campaign thanks to his smartly-taken first-half header.
Guardiola's side failed to win for the first time in 16 Premier League games dating back to last season as a result of the latest VAR row.
Bournemouth condemned Aston Villa to a second consecutive defeat with a 2-1 victory, while Brighton drew 1-1 with West Ham.