French seventh seed Pierre-Hugues Herbert downed Czech Tomas Berdych 6-2 7-5 to reach the final of the Open Sud de France in Montpellier on Saturday. It is Tsonga's first title since he defeated Diego Schwartzman to win the 2016 Antwerp title without surrendering a set.
Tsonga, a former world number five, is now down at 210 in the rankings after a lengthy battle with a knee injury.
Tsonga then opened up a 5-1 lead and the match was beyond Herbert.
In Bulgaria, Russia's Daniil Medvedev captured his fourth career title by beating Hungary's Marton Fucsovics 6-4, 6-3 in the Sofia Open final.
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Pella took the first set in just 27 minutes, but he was broken in his first service game of the second set.
But the Russian enjoyed a change of fortunes this time around as he picked up his fourth career title in straight sets.
With no previous ATP wins before this tournament, the 25-year-old came from a set down to defeat Guido Pella 3-6, 7-5, 6-1.
Pierre-Hugues Herbert has been off to a great start of the season in singles although he will still have to wait for his first ATP title, unable to create more damage with his first serve and get free points that would have kept him in contention longer. He also committed five double faults and saved just four of eight break points, as Medvedev won in 76 minutes.