Arsenal took the lead in the 16th minute.
Once Iwobi's strike deflected into the bottom right corner off defender Terence Kongolo, the visitors rarely looked like relinquishing the points.
Henrikh Mkhitaryan nearly marked his return from seven weeks out with a foot injury with a goal but he could not beat goalkeeper Ben Hamer at the end of a flowing Arsenal move.
Alexandre Lacazette then swept home Ainsley Maitland-Niles' cross from close range before the interval to seal their win.
Huddersfield nearly replied in the 50th minute but Adama Diakhaby's driven effort from a low Kongolo cross was saved comfortably by Bernd Leno.
While Arsenal scored twice, Huddersfield fired off 15 shots to the Londoner's nine and had more efforts on target than the Gunners.
Polar bear 'invasion' sparks emergency
An expert team will be dispatched to the archipelago to assess the situation and prevent the predators' attacks on humans. The military personnel and employees are delivered to workplaces by special vehicles, while the area is patrolled.
Special weather statement calls for mixed bag of weather on Wednesday
Pacific Northwest residents who are more accustomed to rain than snow are digging out from a winter storm and bracing for more. Snow will overspread the area during the mid/late morning on Tuesday , with all of us seeing snow by around noon.
Grammy Awards: Host Alicia Keys unaware show returns from commercial break
In 2001, she won five, including Best New Artist, three awards for her song, "Fallin" and one for Best R&B Album. It reminded me where I come from, but it also reminded me of all the places that I can go.
What does it mean?
The Gunners are now fifth, one point behind a resurgent Manchester United who have been in great form since the appointment of an interim manager, Ole Gunnar Solksjaer who took over from Mourinho.
Huddersfield's survival chances are ever more desperate as a 13-point gap to make up in just 12 matches, considering their nearly total lack of goal threat, appears an increasingly impossible equation.
It was his third Premier League goal of the season, matching his total for last term despite making seven fewer starts.
Unai Emery was impressed with Alex Iwobi's performance in Saturday's 2-1 win at Huddersfield Town, but he still thinks the Nigerian has room for improvement.
Unai Emery says he is confident of sealing a top-four slot after Arsenal secured their first away win since November at Huddersfield.
Unai Emery said he is not anxious that Arsenal failed to keep a first away clean sheet of the season, as first-half goals from Alex Iwobi and Alexandre Lacazatte secured a 2-1 win at Premier League bottom side Huddersfield.