They pointed out that there are running battles in neighborhoods as riot police started using tear gas and live bullets to disperse the protests.
Protests that first erupted in the provinces on December 19 over a government decision to triple the price of bread have swiftly escalated into nationwide rallies widely seen as the biggest threat to Bashir's three-decade rule.
Demonstrations were held in Gadarif, Faw and Amri, as well in the western region of Darfur, activists said, with eyewitnesses adding that police had broken up a 1,000-person strong demonstration in the northern Darfur town of el-Fasher. Today's Anti-Bashir protests also rocked Wad Madani and other areas.
Witnesses told the news agency that security forces used tear gas against dozens of demonstrators in al-Halfaya Bahri, an area in the south of Khartoum, and against a demonstration by dozens of people emerging from Sayed Abdel Rahman Mosque in Omdurman, which sits on the other side of the River Nile from the capital.
Sudan's top Islamist party, a member of President Bashir's government, called on the government not to use lethal force against protesters during the weeks-long demonstrations.
Darfur, a region the size of France, has been torn by violence since 2003 when ethnic minority rebels took up arms against Khartoum, accusing it of economic and political marginalization.
Bashir, who came to power in a military coup backed by Islamists in 1989, has remained defiant amid fears of unrest in the country.
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Senior US officials were shocked too, among them Defense Secretary Jim Mattis, who quit in protest. No U.S. personnel have left Syria yet, according to a Pentagon spokesman.
Ibrahim said that two additional protesters who were being treated in hospital in Gadaraf, an impoverished agricultural town, had passed away, taking the overall death toll to 24.
Human Rights Watch said on Monday that at least 40 people had been killed, including children and medical staff. He has insisted that the protests are part of a foreign plot to undermine Sudan's "Islamic experiment" and blamed the country's worsening economic crisis on worldwide sanctions.
Sudanese officials including Mr Bashir have blamed the violence during demonstrations on "thugs" and "conspirators".
Repeated shortages of food and fuel have been reported in several cities, including Khartoum, while the costs of foods and medicines have more than doubled. It restricted Sudan from conducting global business and financial transactions.
Darfur has remained largely calm since a year ago, with no anti-government demonstration held so far even as protesters staged hundreds of rallies in other cities that have been swiftly broken up by riot police.
The crackdown has drawn worldwide criticism with Britain, Canada, Norway and the United States warning Khartoum that its actions would "have an impact" on its relations with their governments.
Washington imposed a trade embargo on Khartoum in 1997 that was lifted only in October 2017.