Three people are dead and 23 are injured after a double-decker bus filled with commuters crashed into Westboro Station in Ottawa.
Mayor Jim Watson said two of those who died were on the bus and the other was in the shelter.
It is believed that some of those injuries in the crash were critical.
Photos posted on Twitter showed extensive damage to the front of the bus, with the roof of a shelter having carved deep into the vehicle's second deck after the vehicle jumped the curb and plowed along the platform.
Police chief Charles Bordeleau said "several people were trapped on the upper level" of the bus before being freed.
His partner usually gets off the bus at that station when coming home from work but she hadn't gone in on Friday, he said, and now they're checking in with all their family and friends who live in the area to see if they're OK. The driver was questioned by police, he said.
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"Like Ontarians from across the province, I was shocked and saddened to hear of the bad tragedy at Westboro station in Ottawa". He saw first responders cutting out seats and windows from the top floor of the bus and described the front of the bus as being "essentially cut off" or "demolished".
Ottawa Mayor Jim Watson offered his sympathy on Twitter saying, "Our hearts and condolences go out to all those injured, those who lost their lives as well as to their families".
Buses were being detoured as a result of the accident, OC Transpo said.
Brad Muir, a retired sergeant with the Ontario Provincial Police and a collision reconstruction consultant, told CTV News Channel that investigators will be downloading electronic data from the bus and reviewing eyewitness statements, road conditions and video camera surveillance.
The bus has a capacity of 90 people, both sitting and standing.