If the Hammers were bruised from their 4-0 home defeat by Manchester City a week earlier, they did not show it on Tyneside.
Cresswell suffered a hamstring problem in Saturday's 3-0 win at Newcastle, when Balbuena took a knock.
"We need to add points, they are at home and in a good moment but, after this one, we need to play 24 games more".
The centre-back has quickly established himself as a regular in the starting XI and must be one of the first names on the team sheet of boss Manuel Pellegrini.
Pablo Zabaleta got in a vital block on Salomon Rondon's stoppage-time effort, but Newcastle headed for the dressing room knowing they simply had not done enough during the opening 45 minutes.
Hernandez has had only limited involvement this season after being floored by a virus, but his performance at St James' Park suggested he is ready to terrorise defences once again.
"We were too open, and they punished us for it".
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"Our mentality is to understand there are no weaker teams and we have to play our best at all times".
Pellegrini said: "If you review his career, Javier had played at Manchester United, at Real Madrid, at Bayer Leverkusen, in the national squad of Mexico, different countries and everywhere he has scored".
"Of course, we made three or four big mistakes, and West Ham took advantage of that".
"I don't think it is a crucial match for both teams, but it is an important match for both teams".
"After that, we were trying to do everything, but sometimes the anxiety doesn't allow you to make the right decisions".
The task for West Ham the defender feels will be to play with full concentration for the full 90 minutes and not drop important points that they have been dropping this season.
Anderson's pace down the left caused Newcastle all kinds of problems, but it was Mexico worldwide Hernandez who put them to the sword.
"But I know he's a scorer and a player who plays very well inside the 18-yard-box, so I started with him today because before that he was not able to play a complete game".