Hosts Australia are still without two of their best batsmen as former captain Steve Smith and David Warner continue their 12-month long suspension from all forms of cricket for their roles in the ball-tampering scandal that rocked the world of cricket earlier this year.
India's past Test record in Australia is quite abysmal.
Australia won every match of the four-Test series, only the second time India had toured Australia.
Marsh will be sent back to play for Western Australia in the Sheffield Shield but Paine made clear that he was likely to be required later in the series, with pitches in other cities unlikely to provide as much assistance to the bowlers. "We've been rolling our sleeves up, we've got plenty to prove as well".
Marsh's place has been taken by middle-order batsman Peter Handscomb - who has been recalled for the first time since the tour of South Africa in March and April - meaning Australia will rely on three seamers.
But the Indian skipper is insisting he has grown up and will not be looking for confrontations, although he added that "if they want to play a certain way we will reciprocate".
India arrive in Australia as favourites to win the series and its not hard to see why.
When it comes to pace-bowling department, India rarely gets the luxury to be picky.
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In his 10 Test appearances on Australian soil, the lanky seamer has managed just 20 wickets at an average of 62.
"You sense they're smelling blood".
"There were some very tight Test matches and we lost some big moments badly which cost us the series", said Shastri.
India head coach Ravi Shastri on Australia's poor form: "I always believe no team is weak at home". Since they are playing at home, I foresee they will be a lot more closer, and they will be able to combine forces to really score.
"The quicks are going to have to bowl a bit more and we have full faith that Nathan Lyon can do the job in any conditions, he's shown that over the last few years, he bowled a mountain of overs in the UAE and our quicks are fresh so we can cover that, Travis Head bowls some handy offspinners so we have options there but we'll be backing our bowlers".
India named a 12-man squad on Wednesday, having not yet decided whether Rohit Sharma or Hanuma Vihari would claim the final spot in their batting order.
India (from): Virat Kohli (captain), Murali Vijay, Lokesh Rahul, Cheteshwar Pujara, Ajinkya Rahane, Hanuma Vihari, Rohit Sharma, Rishabh Pant, Ravichandran Ashwin, Mohammed Shami, Ishant Sharma, Jasprit Bumrah.