Welbeck has always been Arsenal's go to man on Europa League nights, scoring five goals in his past 13 appearances in the competition, but he looks set for a lengthy spell on the sidelines after landing on his ankle awkwardly.
There was no immediate comment from the club on the seriousness of the injury to Welbeck, whose contract with the north London side ends at the end of the 2018-19 season.
"We worked well with very good commitment in a hard game".
"But when he had the injury we needed to play with a right-back which was the reason we played with Ainsley [Maitland-Niles]".
"We wish him the best and will keep on encouraging and motivating him to get back". But when the match finishes, the first thing they did was ask for him.
"He was working well and he was having a good match", said Emery. They [saw] it was a big injury.
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Jeremy Mathieu was sent off late on for the visitors, and he will miss the next game. "We don't want it, but this is our profession".
In addition to a troubling injury suffered by Danny Welbeck, confirmed by Emery as a leg break, Stefan Lichsteiner was also forced from the pitch with a hamstring complaint.
The 27-year-old has overcome serious issues in the past, missing large chunks of his career with knee problems.
He was carried off the pitch following an awkward landing after he had beaten Sporting defender Bruno Gaspar to a header and it was clear he was in need of help.
"I feel very sorry for Welbeck, he is a great person".
The 6-foot winger has been a revelation since leaving Angers for Lille in 2017, scoring 14 goals in all competitions last season before playing a starring role this term.