A third bomb was hidden in an unmanned vehicle that had been parked at a nearby auto park, police said.
An initial "two blasts struck the perimeter of the Sahafi hotel along the main road... more than 10 people died, a lot of them civilians and some security guards", said police official Ibrahim Mohamed. "The death toll is sure to rise". "Government officials and security forces are always in the hotel", he told Reuters.
Mohamed Abshir from Amin ambulance service told Efe that 14 people were killed, while the ambulance service said on Twitter that it had transported 45 injured people to hospitals.
Somali officials say 20 people died and dozens more were hurt in blasts claimed by Islamist militant group al-Shabab.
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According to sources, the fatalities included the son of the owner of the hotel, Abdirashid Ilqeyte, who was killed in a Shabaab attack on the establishment in November 2015.
"I saw nine dead bodies along the road and they were civilians, some of them riding on rickshaws when the blasts occurred".
The bombs destroyed parts of the hotel perimeter despite layered security, and several shops and other buildings nearby were destroyed. "Most of the dead and wounded were civilians", added Awil Mohamed, another witness.
Al-Shabab said it targeted government officials staying at the hotel.
No group immediately claimed responsibility, but Islamists from the al Qaeda-linked al Shabaab group have mounted regular attacks in the capital.