Julen Lopetegui and Santiago Solari have both gone with Keylor Navas for the Copa del Rey and the UEFA Champions League whereas Thibaut Courtois has been preferred to the Costa Rican in the league matches.
"I think we played a very nice game today, we scored wonderful goals", Solari told reporters.
Navas started Madrid's three European fixtures under previous boss Lopetegui but was among the substitutes for Wednesday's victory, which saw the reigning champions rise to the top of Group G, but Solari said he's made the choice to go with Courtois.
The victory also marked Real's third in a row in all competitions under their temporary coach, who said he was focused on the next game rather than his status at the club.
The La Liga side can qualify for the knockout stages with a draw against Roma in their next game, should CSKA Moscow fail to beat Plzen. CSKA have four points with Plzen on one.
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Casemiro guided a simple second into the corner of the net after being left totally unmarked from a corner, before Benzema helped himself to another in nearly identical circumstances, this time once picked out by Gareth Bale's headed pass four yards out.
Four of Los Blancos' goals came in a 19-minute spell in the first half, having struggled up until that point, and Toni Kroos added a fifth after the restart.
Let us take a look at the possible Real Madrid line-up which will try to grab a win against Viktoria Plzen.
But any hopes Plzen harboured of a shock win were wiped out with two quickfire goals in the 21st and 23rd minutes.
Real Madrid full-back Dani Carvajal has hailed recently-sacked Los Blancos coach Julen Lopetegui as the best he has ever worked with. Once they play with this seriousness, commitment and wanting to score.
Real Madrid signed Thibaut Courtois from Chelsea in the summer after the Belgium global had a sensational World Cup in Russian Federation with his national team.