Mrs. Trump says she expects the visit to be "very emotional".
SA-born comedian Trevor Noah has weighed in on Mama Trump's tour of Africa questioning why she is here to teach us about the evils of cyberbullying when so many do not even have internet access.
The US First Lady cuddled some babies at the hospital, before also donating a phototherapy machine, teddy bears and assorted baby items.
Melania was clearly very fond of last year's look, because she paired the jacket with a near-identical ensemble for her trip to Cape Coast Castle, a former slave trading fort that is located around 90 miles from the Ghanaian capital of Accra.
The U.S. first lady spent about an hour on a guided tour of the 17th-century castle, where slaves were held before they were shipped across the Atlantic Ocean.
Before proceeding to the slave castle, she visited the palace of the head chief of the area and obtained royal approval to visit the fortress after presenting drinks to the chiefs.
She arrived in Ghana on the first stop of her first solo global trip as first lady, a tour of Africa, a continent her husband has been reported to have referred to derisively.
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Donald Trump says it is ‘a scary time for young men’
Ford identified other witnesses to the event, and those witnesses either refuted her allegations or failed to corroborate them". I don't know the other boy's name. "They'll make their decisions", Mr Trump said . "And a man's life is in tatters", he added.
But unlike her predecessors, Melania Trump's tour will be followed closely to see if she can build bridges after her husband's apparent disparaging comments.
Melania, who has so far spent her time in Africa visiting children in schools and hospital patients, said the castle is 'really something that people should see and experience'.
President Donald Trump told reporters on the South Lawn of the White House on Tuesday that he saw television footage of her landing in Africa.
Mrs Trump, who was born in Slovenia, is on her first visit to Africa, with a goal of highlighting child welfare on the continent. She walked through the infamous "Door of No Return".
The women met for the first time at the UN General Assembly last month at which President Trump railed against globalism, earning him stern rebukes from world leaders.
The first ladies met privately for about a half-hour at Jubilee House, Ghana's presidential palace.
Trump is also scheduled to visit Kenya, Malawi, and Egypt where she will discuss her Be Best campaign to raise awareness of cyberbullying.