The network is billing it as the first lady's first sit-down interview, although she briefly spoke to CNN's Kate Bennett during last year's trip to China, while they were both standing on the Great Wall.
First Lady Melania Trump was nearly knocked down by a baby elephant on Friday while on safari in Nairobi National Park in Kenya.
It may not have been the most glaring faux pas the hyper-scrutinized Trump has ever made. "I thought I wasn't going to have a chance to see her".
She was briefed on the children living at the house for babies.
Melania's visit, which started in Ghana and will continue on to Kenya and Egypt, has so far attracted varied interest levels in Africa with few crowds lining streets to see her.
The criticism was not universal.
She had the opportunity to get up close to a baby elephant, and photographs show her smiling warmly at the animal. "It is a attractive thing to see".
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Melania and her host are expected to head to State House for talks before going to the Kenya National Theatre where they will be treated to Kenyan creative cultural performances. "It's exhausted and it's old and it's inaccurate".
Mrs Kenyatta runs the Beyond Zero campaign, a health initiative for expectant women while Mrs Trump launched Be Best initiative to improve the welfare of children.
While in Ghana, Trump met with her counterpart, Rebecca Akufo-Addo. The U.S. Fish and Wildlife Service, an agency of the Department of the Interior, claimed that lifting an existing ban on elephants imported from Zimbabwe and Zambia and encouraging wealthy big-game hunters to kill the threatened species would help raise money for conservation programs. She delighted in holding babies and held hands with older children, who sang and danced. And with Washington imploding over a battle to confirm Brett Kavanaugh, the president's nominee for the Supreme Court, Melania Trump seemed free of the usual scrutiny that nips at her stilettos in Washington.
Mrs. Trump opened her first extended global tour as first lady on Tuesday in the West African nation of Ghana.
She added, "Who advised you?" She emerged without a smudge.
The elephant park was said to be her favourite part of the trip.
Dressed in riding pants, boots and a white safari hat, she took photos and peered through binoculars for a closer look at zebras, giraffes, impalas, rhinos and hippos.
"It's like showing up to a meeting of African-American cotton farmers in a Confederate uniform", Matthew Carotenuto, a coordinator of African Studies at St. Lawrence University, wrote on Twitter. A boy read a story to her in turn.