The patient, only the second in the United Kingdom to be diagnosed with the rare viral infection, was quarantined before being transferred to Liverpool, which specialises in tropical diseases - and bosses at the Vic have moved to stress patients, staff, and visitors are no longer at risk.
"When tests confirmed it was the Monkeypox virus the patient was transferred to Liverpool as per our standard guidelines".
However, Public Health England have stressed that the cases are unrelated.
The second patient was being treated in the tropical and infectious diseases unit of Royal Liverpool University hospital.
Dr Michael Jacobs, clinical director of infection at the Royal Free Hospital said in a government statement: "Monkeypox is, in most cases, a mild condition which will resolve on its own and have no long-term effects on a person's health".
A painful rash with open sores can develop, often beginning on the face, then spreading to other parts of the body.
Dr Nick Phin, the deputy director of PHE's national infection service, said monkeypox was probably still circulating in Nigeria after an outbreak there a year ago.
The PHE said that people who have no symptoms are not considered infectious.
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"A Technical Working Group coordinated by NCDC and comprising of partners from the Federal Ministry of Agriculture and Rural Development, World Health Organisation (WHO), UNICEF and U.S. Centres for Disease Control (US-CDC)". And like they do with other members of the Orthopoxvirus genus, monkeypox infections in humans onset with the characteristic flu-like symptoms of fever, headache, muscle pain, chills, fatigue, and swollen lymph nodes.
Symptoms usually appear about two weeks after a person is exposed to monkeypox.
'The patient is being cared for on our specialist infectious and tropical diseases unit, by highly trained staff who are experienced in dealing with a variety of infectious diseases.
The illness has been reported mainly in central and west African countries.
Monkeypox is known to have a wide-ranging incubation period of anywhere between five and 21 days, per the Centers for Disease Control and Prevention, and transmits chiefly through direct contact with infected animals.
Most people recover within several weeks, says PHE.
"Public Health England is following up those who have had close contact with the patient to offer advice and to monitor them as necessary".
"Since the re-emergence of Monkeypox in Nigeria in September 2017, NCDC has continued to receive reports and respond to cases of the disease from states across the country", he said.