Melania's visit to McAllen comes amid the bipartisan backlash over the Trump administration's enforcement of a "zero-tolerance" policy - criminally prosecuting migrants who cross the US-Mexico border.
While the jacket is now unavailable, the military-style coat, which was sold at Zara two years ago, originally retailed for $39.
In the past, the First Lady has worn designs by Christian Dior, Givenchy and Valentino, Dolce & Gabbana, often paired with Christian Louboutin shoes.
Trump changed into a different jacket before her plane landed in McAllen, Texas.
Colbert responded to the comments from Grisham about there being "no hidden message". In an attempt to deflect criticism targetted at Melania for her sartorial choice, President Trump sought to link the quote on her dress with "fake news".
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Melania Trump’s Jacket: "I Really Don’t Care, Do U?"
They had signed an American flag to give the first lady as a gift, but she chose to sign it and leave it for the kids to keep. The First Lady's spokesperson has said in a statement of the jacket, "It's a jacket...there was no hidden message".
"I'm here to learn about your facility, in which I know you house children on a long-term basis", Trump said during her visit. Trump tweeted. News of the first lady's surprise visit made a media splash on the heels of Trump's decision to end family separation with the power of the pen in an executive order.
In fact, a quick search of the words "I really do care" on Etsy reveals a ton of merchandise, from T-shirts to buttons, seemingly created in response to the first lady's jacket.
The youthful jacket sharply contrasts with the first lady's typically bold wardrobe. She told children to "be kind and nice to each other" as she left another classroom. "Melania has learned how dishonest they are, and she not longer cares!"
One day after President Donald Trump signed an executive order to stop separating migrant children from their families at the US border, First Lady Melania Trump decided to make a spontaneous trip to Texas to meet with the detained children. The first lady signed it as well. "DO U?" on her tour of an immigrant children detention center in Texas. "She is so low-maintenance, so efficient, that she does everything herself", Reynolds said.
One social media user said the incident should prompt people to donate to organisations advocating for immigrant children and their families. "And I'm going to guess this was one message she did not steal from Michelle Obama".