A Metropolitan Police statement said: "The victim was stationary in his vehicle when two males on a moped smashed the auto windows with a hammer before stealing property".
He was then said to have run around to the passenger side of the vehicle to comfort his 10-year-old son who was leaving school.
McIntyre is a stand-up comedian and is host of Saturday night entertainment series Michael McIntyre's Big Show.
Police said the moped riders stole property - thought to be the comedian's watch.
In pictures obtained by the publication, Michael was seen rushing to the passenger side of the auto to comfort his son. Michael fell but he was still trying to put up a fight. It was all so quick - the whole thing must have taken 30 seconds.
'And then within seconds they were gone down the hill.
According to The Sun, which had pictures of the smashed auto window and a shaken McIntyre talking to police, the comic was on the school run when he was attacked.
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McIntyre, 41, lives in Hampstead, north London, with his wife of 15 years Kitty, who works as an aromatherapist.
Others to have fallen victim to so-called moped gangs include MoneySavingExpert.com founder Martin Lewis, whose phone was snatched from his hands last July, while actor Daniel Radcliffe came to the aid of a tourist who was mugged. No injuries were reported.
The comedian's agent confirmed there was an incident, but told the newspaper: "He is absolutely fine".
Michael McIntyre's 2012 tour included a record-breaking 10 nights at The o2 Arena in London, and played to over 700,000 people nationwide.
No arrests have been made and police are asking that anyone with information about the incident should call 101 quoting CAD4018/04JUN or Crimestoppers anonymously on 0800 555 111.
Witnesses were asked to contact police.