On April 18, the Nicaraguan army shot at people protesting reforms to the country's pension plan.
The United States Embassy in Managua, Nicaragua confirmed the death of the American whose was found killed Saturday morning in the Rubenia sector. The incident killed 15 people, 218 people were injured.
Nicaragua's Catholic bishops have tried to broker a peaceful solution to the unrest but the dialogue broke down when the bishops withdrew from their role as mediators, citing "a lack of consensus among the parties".
Mother's Day protests in Nicaragua turned deadly on Wednesday as government forces opened fire on protesters, killing over a dozen people and injuring many more.
"The aggressors were the repressive police and shock forces" who report to Ortega and his wife, according to the rights group.
But as Ortega - who lost the presidency in a 1990 election - charted his eventual return to power in 2007, he courted the cardinal's favor with a mix of progressive social policy and support for a total abortion ban.
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"The anti-democratic reality of which Nicaraguans are victims is sustained and aggravated", said the former presidents, including Colombia's Andres Pastrana, Mexico's Felipe Calderon, and Spain's Felipe Gonzalez, part of the Democratic Initiative in Spain and the Americas.
The government and opposition had agreed on Monday to resume peace talks mediated by the Catholic Church that stalled last week. The march had been promoted as a peaceful demonstration by organizers.
"(We) condemn all of these acts of repression on the part of groups close to the government and we want to leave it clear the national dialogue talks can not continue while the Nicaraguan people continue being denied their right to protest", the prelates said.
Recently a group of mothers of those killed by pro-government forces were attacked at a protest by police and pro-government forces. Gunmen firing into crowds sent thousands of demonstrators running for cover at the marches, which were led by mothers of victims who died in recent protests.
"From my point of view, and it is something largely shared in the private sector, we must find an orderly way out of this, in a constitutional way, which implies reforms including a (presidential) election moved forward" from 2021, he said in an interview with newspaper La Prensa.