"Relief from sanctions will come only when we see tangible, demonstrated, and sustained shifts in Tehran's policies", Mr. Pompeo said. "These will indeed end up being the strongest sanctions in history", Pompeo said.
"U.S. diplomacy sham is merely a regression to old habits: imprisoned by delusions & failed policies-dictated by corrupt Special Interest-it repeats the same wrong choices and will thus reap the same ill rewards".
"The United States wants to withdraw from an global multilateral agreement, and then, under other circumstances, it wants to negotiate and reunite", Qassemi said, according to Iran's Fars News Agency. European Union officials are reportedly exploring the possibility of widening the scope of the 2015 deal to include Iran's missile programme.
"Our demands on Iran are not unreasonable: give up your program", Pompeo said in a speech outlining demands on Iran.
Taken together, the demands would require a complete transformation by Iran's government, and they hardened the perception that the administration is really seeking regime change. He warned of "the strongest sanctions in history" if Iran doesn't change course.
"A guy who had been active in an espionage center for years now wants to make a decision for Iran and other countries from the position of a foreign minister".
Pompeo also offered Iran a series of potential USA concessions.
Trump has long said the 2015 nuclear deal with Iran - also signed by the United States, Britain, China, France, Germany, and Russian Federation - did not go far enough.
The top diplomat said that "Iran would be battling to keep its economy alive" after the sanctions take effect.
Once-missing teachers, students among ones killed in Santa Fe shooting
Meanwhile, students were being let back inside Santa Fe High School to gather belongings they abandoned when the gunfire began. All schools in the Santa Fe school district will remain closed on Monday and Tuesday, officials said at a short briefing.
Royal wedding celebrity guest arrivals: The best hats, fashion and photos
Meanwhile, British actor and Luther star Idris Elba posted a photo of him and his fiancee Sabbi Dhowre heading to the wedding. Guests have begun making their way to the St George's Church to witness Prince Harry and Meghan Markle's wedding.
Golden Knights' James Neal hails 'amazing' Vegas crowd
Only seconds after costing his team the lead with a penalty, Tomas Nosek scored to hand Vegas the lead back on his next shift. Dozens more fans arrived in Las Vegas on flights Thursday to be in town in time for Game 4 Friday night.
In the aftermath of the U.S. withdrawal from the 2015 nuclear agreement with Iran, Secretary of State Mike Pompeo in his first major foreign policy speech demanded major changes from Iran and said America will not allow the country to develop a nuclear weapon: "Not now, not ever".
On May 8, Trump announced his decision to withdraw the United States from nuclear deal despite efforts by the European allies to convince him to stay in the 2015 agreement. None of this is news, and his speech left huge questions about the Trump administration's "new Iran strategy" unanswered.
'Iran's leaders saw the deal as a starting gun for the march across the Middle East, ' Pompeo said.
They include an end to uranium enrichment, "unqualified access" for inspectors, a halt to support for Houthi rebels in Yemen, the withdrawal of all forces from Syria, removal of backing for ally Hezbollah and no more threats to Israel. "Any new agreement will make sure Iran never acquires a nuclear weapon and deter the regime's malign behavior in a way that the JCPOA never could".
Pompeo also demanded that Iran cease from a range of activities throughout the Middle East that have long drawn the ire of the USA and its allies. He says the deal "put the world at risk because of its fatal flaws".
But in his remarks at the Heritage Foundation, Pompeo said only that if Europe wanted to try to preserve the Iran deal working with Tehran, that would not change the Trump administration's approach.
"Looking forward to speaking [at Heritage] on Monday, May 21, about the road ahead on [Iran]", Pompeo tweeted over the weekend.
British Foreign Secretary Boris Johnson cast doubt that the broad list of objectives can be achieved in "a reasonable time frame", as Pompeo described.
European allies of the USA are growing increasingly frustrated over Trump's decision to pull out from the deal.