Perdomo had also hit Trevor Story to load the bases with two outs in the first inning. In the top next half inning, Colorado's German Marquez did the same San Diego's Hunter Renfroe.
Perdomo threw his glove at the oncoming Arenado before backtracking and putting his fists up for a fight.
Rockies third baseman Nolan Arenado did more fighting today than National Basketball Association players have done all season.
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Colorado Rockies Third Baseman Nolan Arenado wasn't having any of it Wednesday afternoon when a throw by San Diego Padres Luis Perdomo came dangerously close behind him. A bench-clearing brawl quickly ensued that would see two Padres, the battery of AJ Ellis and Perdomo, and three Rockies ejected: Arenado, German Marquez, and Gerardo Parra. The benches cleared and relievers ran in from the bullpen.
According to Yahoo Sports, in seven games between the two teams this season, six different batters have been hit by a pitch including A.J. Ellis, Christian Villanueva, Jose Pirela and Manuel Margot, who were beaned prior to today's game.
It actually makes Arenado's dodge of Perdomo's throw even more impressive. Arenado was the leadoff hitter in the third inning with the game tied 0-0, before the fireworks erupted. The Rockies head east to take on the Washington Nationals beginning on Thursday night in a four-game series.